Yisong Guo

Yisong (Alex) Guo currently works at the Department of Chemistry, Carnegie Mellon University. Alex does research in the fields of  Bioinorganic Chemistry, Spectroscopy, Chemical Kinetics and protein Biochemistry. The group's main research focus is iron containing metalloproteins, in particular, small molecule (N₂, H₂, O₂ etc.) activating enzymes, such as nitrogenases, hydrogenases, and oxygenases. Various advanced spectroscopic methods are utilized to gain information regarding iron center changes, both geometric and electronic, during enzyme catalytic cycles. Spectroscopic studies are coupled with Density Functional Theory (DFT) calculations to establish structural models and further identify reaction mechanisms. The ultimate goal of our research is to impact favorably on alternative energy research and human health.